Pigmented Perivascular Epithelioid Cell Tumor (PEComa) of the Kidney: A Case Report and Review of the Literature
نویسندگان
چکیده
Heavily pigmented perivascular epithelioid cell tumors (PEComa) are rare, only eight cases of which have been reported. Unlike typical epithelioid angiomyolipoma, most of these tumors have been encountered in female patients without tuberous sclerosis. The long-term prognosis thereof is undetermined. Cytological similarity and heavy melanin pigment make it difficult for pigmented PEComa to be differentiated from pigmented clear cell renal cell carcinoma or malignant melanoma. The immunoprofile of tumor cells, such as human melanoma black-45 expression, as well as the absence or presence of other melanocytic or epithelial markers, are helpful in determining a differential diagnosis. Here we report a case of heavily pigmented PEComa of the right kidney and review the literature describing this tumor. In this case, the immunoprofile and clinical features corresponded well to those described in the literature. Since the prognosis of such disease has not yet been established, close follow-up of this patient was recommended.
منابع مشابه
Pigmented perivascular epithelioid cell tumor (PEComa) arising from kidney
INTRODUCTION Perivascular epithelioid cell tumor (PEComa) is a mesenchymal neoplasm composed of perivascular epithelioid cells with clear to eosinophilic cytoplasm. Pigmented PEComa arising from kidney is extraordinarily rare and sometimes can exhibit aggressive biological behavior. CASE REPORT We present here a rare case of pigmented renal PEComa in a 46-year-old female. The patient had comp...
متن کاملPrimary Perivascular Epithelioid Cell Tumor (PEComa) of the Liver - A Case Report and Review of the Literature -
Perivascular epithelioid cells (PECs) were initially proposed, by Bonetti et al. in 1992, to describe an “unusual atypical cell type” of epithelioid shape and harboring a clear to eosinophilic cytoplasm with perivascular distribution in both renal angiomyolipoma (AML) and clear cell sugar tumor (CCST) of the lung. This perception gradually became accepted and led to the concept of perivascular ...
متن کاملPrimary perivascular epithelioid cell neoplasm of thigh bone: a case report and literature review
Primary perivascular epithelioid cell tumor neoplasm (PEComa) of bone is extremely rare. To our knowledge, only 11 cases of PEComa primarily arising in bone have been described. Herein, we present one case of primary bone PEComa which occurs in the thigh.
متن کاملNasal Angiomyolipoma (AML) Mimicking Juvenile Nasopharyngeal Angiofibroma
Introduction: Angiomyolipoma (AML), a benign mesenchymal tumor that commonly arises from the kidney, may be associated with tuberous sclerosis complex and perivascular epithelioid cell tumors (PEComas). Nasal angiomyolipoma is very rare and usually occurs in elderly individuals with epistaxis and nasal obstruction. Case Report: We report a rare case of nasal angiomyoli...
متن کاملImproving recognition of hepatic perivascular epithelioid cell tumor: Case report and literature review.
A 58-year-old man presented with the chief complaint of abdominal bloating and was incidentally found to have a liver tumor. As diagnostic imaging studies could not rule out malignancy, the patient underwent partial resection of segment 3 of the liver. The lesion pathologically showed eosinophilic proliferation, in addition to immunohistochemical positivity for human melanoma black 45 and Melan...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 46 شماره
صفحات -
تاریخ انتشار 2012